Lovenox is an anti-coagulant medication which prevents formation of harmful blood clots that can leads to heart attack or stroke. Manufactured by Sanofi-Aventis, Lovenox keeps the blood flowing smoothly by reducing the activity of blood clotting proteins. The risk of developing blood clots more commonly occurs after knee or hip replacement surgeries or after heart attack or chest pain known as unstable angina. Approved by majority of the drug regulatory authority, Lovenox is prescribed for extended prevention of deep-vein thrombosis (DVT) that is likely to occur after hip replacement surgery. DVT is a blood clot that develops in the veins and require specific drug like Lovenox to treat this problem. Lovenox alter the normal blood clotting process and hence, the clots cannot be easily formed. This drug is the first low-molecular-weight heparin that can be used by the patients even at home.
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Enoxaparin Sodium is the active ingredient present in Lovenox and the inactive ingredients present in the drug include benzyl alcohol and water.
Lovenox is a low molecular weight heparin drug which prevents blood clot formation by binding to anti-thrombin III enzyme in the body. To understand the exact mechanism of Enoxaparin, one needs to understand the process of blood clot formation. Usually a blood clot is formed to stop bleeding that occurs due to injury to the tissues. Blood clotting process starts with platelets clumping together and producing chemicals that activate the clotting process. Clotting process later involves a substance thrombin which is activated to produce a protein fibrin. This fibrin binds the platelets together to form a blood clot. Thus, Enoxaparin is prescribed to prevent and treat abnormal blood clots that work by inactivating thrombin in the blood clotting process. This also stops the formation of fibrin which is an essential component of blood clot formation.