Cornell University researchers develop method of growing tumor cells spherically to enhance drug testing
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Recently, a team of Cornell University scientists found a way to force tumor cells to grow into 3D spheres, which could lead to the development of more accurate tests for new cancer therapies.
Lead author Michael R. King and his colleagues believe that these shapes provide a realistic, easily accessible substrate on which to test new drugs for efficacy. This is important because in the human body, tumor cells grow in 3D, but most laboratory studies have been done in 2D on a flat petri dish.
"Basically, any laboratory that works with cells could adopt our new spherical microcavity system to do their own 3D experiments or drug screening on hundreds or even thousands of little tumor spheroids," King explained.
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