Early onset bipolar disorder tied to rare mutations
While adults can help themselves cope with bipolar disorder if they buy Canadian Zyprexa, few people are aware that children and young adults may also be prone to this disease.
While adults can help themselves cope with bipolar disorder if they buy Canadian Zyprexa, few people are aware that children and young adults may also be prone to this disease. However, researchers from the University of California in San Diego discovered that a rare genetic mishap may make younger people prone to early onset bipolar disorder.
De novo copy number variants (CNVs) occur when there are too few or too many copies of a certain section of DNA, according to the scientists. De novo mutations happen spontaneously and are not inherited from one's parents.
Based on evidence that CNVs may be tied to schizophrenia and autism spectrum disorders, the researchers investigated whether these mutations also played a role in early onset bipolar disorder. Their data analyses showed that CNVs play a major role in the development of the condition for 5 percent of patients with the disease, as published in the journal Neuron.
While this study does not implicate any specific genes, finding a relationship to CNVs is still vital information, according to the researchers, who add that further studies that sequence the DNA bipolar individuals and their families are needed to determine all genetic influences.
At least 50 percent of cases of bipolar disorder manifest before the age of 25, according to the National Institute of Mental Health.
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