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Lipitor, Celebrex combination is safe in prostate cancer therapy



People who need medication to control their cholesterol levels or symptoms of arthritis can buy cheap products through a Canadian pharmacy.

People who need medication to control their cholesterol levels or symptoms of arthritis can buy cheap products through a Canadian pharmacy. A combination of two of these drugs - specifically, Lipitor and Celebrex - may provide a safe and effective treatment for prostate cancer in the future, based on a clinical trial conducted by the Cancer Institute of New Jersey.

Previous research suggested that either of these two drugs can block a protein complex known as NFkB, which plays a role in the growth of tumor cells. In order to evaluate the effects of a combination of these medications on prostate cancer, the study team conducted an experiment on 16 men who developed localized prostate cancer that recurred after an initial treatment.

For six months, subjects took two Celebrex pills and one Lipitor pill every day.

Preliminary results showed that while the regimen was safe, patients demonstrated lower levels of prostate specific antigen, which is a marker for cancer in the organ, as presented at the 2012 Genitourinary Cancers Symposium.

"While additional research is needed, this study is helping us better understand the mechanisms behind tumor activation and growth in prostate cancer. As a result we may be able to better identify effective therapies for recurrent prostate cancer," said researcher Mark Stein, MD.

Using medications already approved by the U.S. Food and Drug Administration may bring therapy faster to the clinic compared to new agents, Stein added.

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