New findings shed light on what causes rheumatoid arthritis
Rheumatoid arthritis patients who buy Euflexxa to alleviate their symptoms may be pleased to learn that scientists have made significant findings that shed light onto the cause of the disease.
Rheumatoid arthritis patients who buy Euflexxa to alleviate their symptoms may be pleased to learn that scientists from Mount Sinai Hospital, the University of Toronto, McGill University and the University Health Network have made significant findings that shed light onto the cause of the disease, as well as that of other autoimmune disorders like lupus and type 2 diabetes.
Lead author Katherine Siminovitch and her colleagues published their results in the journal Nature Genetics, in which they reported the exact means by which a mutated PTPN22 gene increases a patient's likelihood of developing rheumatoid arthritis.
In a mouse model, the researchers demonstrated exactly how alterations in this gene can impair the function of immune cells, thereby making it possible for autoimmune conditions to take place.
"Measuring levels of this protein will help us monitor disease severity in patients with autoimmune disorders, test the effects of various therapies including new drugs, and determine which treatments work best in specific patients," study co-author Edward Keystone, who directs the Rebecca MacDonald Centre for Arthritis and Autoimmune Disease at Mount Sinai Hospital, explained. "We are truly seeing genomics in action with this study, and the results give us new hope for improving patient outcomes."
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