Some breast cancers are caused by the male hormone androgen
Many women with breast cancer buy Tamoxifen to slow the progression of the disease and improve their chances of experiencing a positive outcome.
Many women with breast cancer buy Tamoxifen to slow the progression of the disease and improve their chances of experiencing a positive outcome. According to a recent study from the Dana-Farber Cancer Institute, the male hormone androgen may be responsible for the proliferation of some breast tumors in female patients.
Senior author Myles Brown and his team published their findings in the recent issue of the journal Cancer Cell, which explained that drugs that block androgen-activated proteins could slow tumor growth in many women for whom Tamoxifen may not be successful.
"We've identified a novel subtype of breast tumor which grows in response to androgen but not estrogen, and have uncovered the signaling pathways involved in its growth," Brown explained. "We've demonstrated that drugs capable of blocking these pathways, including the receptor for androgen itself, can inhibit tumor growth."
An estimated 75 percent of breast tumors are caused by estrogen. These cancers have cells packed with estrogen receptors, which trap the hormone, promoting the growth and proliferation of the disease.
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